Search results for "sun exposure"
showing 4 items of 4 documents
Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin
2020
Human skin pigmentation results from the enzymatically controlled synthesis of melanin pigments in specialized organelles (melano‐somes) produced within epidermal melanocytes, followed by their transfer to neighboring keratinocytes and their distribution through‐out the epidermis.1 Constitutive skin pigmentation seems to be mostly genetically determined,2 being altered by numerous intrinsic and extrinsic factors affecting the epidermal melanin unit
Evidence of a significant vitamin D deficiency among 9–13-year-old Polish children: results of a multicentre study
2018
Purpose To evaluate the extent to which the population of Polish preadolescents is vitamin D deficient and to assess seasonal variations in vitamin D status. Participants and methods A total of 720 healthy children aged 9–13 years (409 girls, 311 boys) residing in 6 representative geographical locations in Poland were studied. A parental-assisted questionnaire provided data on nutritional habits, vitamin D supplements and sun exposure. Serum concentration of 25-hydroxyvitamin was determined twice, after the winter in March and after the summer in October. Results In March, vitamin D deficiency (25–50 nmol/L) was found in 64%, and severe deficiency (< 25 nmol/L) in 20.2% of children. In Octo…
Light exposure of the lower leg as a pathogenetic factor in the occurrence of malignant melanoma.
1992
Of the 1,198 women and men studied in Mainz from 1966 to 1987 there was an approximately fivefold increase in the incidence of melanoma. Among the men melanomas on the trunk (59.9%) predominated, whereas among the women melanomas on the extremities (40.0%) were more common, especially on the lower leg (26.3%). Comparing the decades 1966-1976 and 1977-1987 there was a significant decrease in melanomas affecting women's lower legs (1966-1976: 33%,; 1977-1987: 24.2%). Fashion-dependent sun exposure of this body area might offer an explanation. It could be demonstrated that common stocking materials do not sufficiently protect against UV radiation (average permeability for UV light about 55%), …
Skin surveillance attitudes and behaviors in relation to skin checks for early signs of skin cancer in a sample of secondary school students and teac…
2012
<p><strong>Background</strong>: Malignant melanoma (MM) can be readily treated in its earliest stages: survival rate, when detected early, is up to 95,0%. This justifies investigations on contributive factors and measures for precocious detection of skin tumors to improve early detection and to increase survival rates. The purpose of this survey was to collect information about knowledge, attitudes and behaviors on prevention in relation to skin checks for early signs of skin cancer on a sample of secondary school students and teachers.</p><p><strong>Methods</strong>: A sample of secondary school students and teachers from Palermo, was recruited usi…